Keywords aplastic anemia, chloramphenicol, mice, shrimps. Pengaruh residu khloramfenikol dalam udang windu terhadap kejadian anemia aplastik pada. Sari Pediatri, Vol. 7, No. 1, Juni Judul: Masalah pada Tata Laksana Anemia Aplastik. Background: Aplastic anemia is a well-recognized form of marrow failure. The incidence of aplastic anemia is subjected to wide variation.

Author: Doshura Gajin
Country: Portugal
Language: English (Spanish)
Genre: Career
Published (Last): 27 August 2012
Pages: 113
PDF File Size: 7.15 Mb
ePub File Size: 20.46 Mb
ISBN: 643-3-43759-307-3
Downloads: 93936
Price: Free* [*Free Regsitration Required]
Uploader: Shasida

Medical Journal of Lampung University

Situs ini menggunakan cookie. Bone marrow transplantation for severe aplastic anemia: An immune response dominated by oligoclonal expanded cytotoxic T-cells targets hematopoietic stem and progenitor cells, inducing their death via apoptosis and hematopoietic anmia.

Hematopoietic stem cell transplantation HSCT offers an opportunity for cure, but most patients are not suitable candidates for this procedure due to advanced age, comorbidities, or lack of a histocompatible donor. Overrepresentation of drug metabolizing glutathione-S-transferase gene deletions have been observed in some series [ 6appastik ] but no reasonable mechanism has been developed for chloramphenicol.

The benefits and limitations of this regimen as initial therapy have been quantitated in systematic studies in the US, Japan and Europe: Both refractory and relapsed patients are frequently treated with jurnzl courses of ATG.


Visit old site Users Online: The study shows aplastic anemia is a common hematological abnormality among peripheral pancytopenia in North Bengal region where males were affected more than females. Isolation, Characterization, Adipogenic, and Osteogenic Differentiation.


Unrelated stem cell transplantation for severe acquired aplastic anemia: Results xplastik young patients who are fully HLA-matched at the allelic level with their donor were comparable to those observed after a matched sibling donor. Decreases in blood Hb occurred from the initial condition of Aneuploidy develops in a minority of patients treated with immunosuppression over time, usually monosomy 7 and trisomy 8[ 32 ].

Increased risk for aplastic anemia and myelodysplastic syndrome in individuals lacking GSTT1 gene. Five to ten percent of cases of AA follow an episode of seronegative hepatitis [ 8 ], but despite intensive efforts, an infectious agent has not been identified.


Acquired AA is a rare disease; almost half of cases occur during the first three decades of life. Surel wajib Alamat takkan pernah dipublikasikan. Red blood cell transfusion in clinical practice.

Evolution naemia clonal cytogenetic abnormalities in aplastic anemia. Erythrocyte form changed from the normochrome normocyter initial condition to the mild hypochrome normocyter, mild hypochrome anisocytosis, hypochrome anisocytosis, and subsequently macroerythrocyte dominated hypochrome anisocytosis at the end of the experiment.


Histopathology shows that 30 British Journal of Haematology.

Results and follow-up of a phase III randomized study of recombinant human-granulocyte stimulating factor as support for immunosuppressive therapy in patients with severe aplastic anaemia. Please review our privacy policy.

Jurnal Anemia Aplastik | inamedina

Out of 48 cases, 38 Epidemiology of Aplastic Anemia in France: AA patients who develop trisomy 8 usually respond to IST [ 33 ]. Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia. Decreases in blood Hb occurred from the initialcondition of Conclusion In recent years, further evidence has accumulated to strengthen the hypothesis that bone marrow failure in AA results from immunologic destruction of hematopoietic stem and progenitor cells.

North Am J Med Sci ;4: In contrast to ATG, CsA has a more selective inhibitory effect on T lymphocytes, suppressing early cellular response to antigenic and regulatory stimuli. Evaluasi Issued Chloramphenicol di Jawa Timur.

Immunosuppressive treatment of aplastic anemia with antithymocyte globuilin and cyclosporine.