Adhatoda vasica belonging to Acanthaceae family, commonly known as Adosa, Adhatoda vasica Flowers, Antibacterial activity, Antifungal activity, Diffusion. Abstract. The present study aimed to evaluate the in vitro antimicrobial activity of pharmacologically important Adhatoda vasica plant extracts. Antibacterial activity of leaf extract of Adhatoda vasica was studied against Bacillus subtilis, Antibacterial activity was determined by disc diffusion method.

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Antibacterial Activity of Leaf Extracts of Adhatoda vasica – MAHE Digital Repository

The alkaloid Vasicine was isolated from ethanolic extract of the leaves of A. Investigation on antifeedant and anthelmentic potential of Adhatoda vasica nees. The combined chloroform extract was washed with water, dipped, and dried over anhydrous sodium sulphate. The compound showed prominent cytotoxic activity in vitro against A lung adenocarcinoma cancer cell line.

Antimycobacterial activity of two natural alkaloids, vasicine acetate and 2-acetyl benzylamine, isolated from Indian shrub Adhatoda vasica Ness. Vasicine hydrochloride, a new drug for interruption of pregnancy.

Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Publications and Information Directorate; The required concentrations, Council of Scientific and Industrial Research; Or and antimycobacterial activities of methyl caffeate isolated from Solanum torvum Swartz. Published online Jan Support Center Support Center. The radical scavenging activity of Vasicine acetate at different concentrations is shown in Table 3.

Journal of Obstetrics and Gynaecology of India. Vasicine acetate showed minimum inhibitory concentration antibacteial against bacteria: Nature acts as a prominent reservoir for new and novel therapeutics. Introduction Natural products still remain the most important source for discovery of new and potential drug molecules.


Kulkarni [ 24 ] reported that A. Then the residue was crystallised from chloroform to get Vasicine acetate activitj colorless crystals m. Negative control was prepared using respective solvents.

Indian Journal of Medical Research. International Journal of Green Pharmacy.

In vitro antibacterial activity of selected medicinal plants from lower Himalayas.

After various durations of cultivation, the solution in the medium was removed. The worldwide threat of antimicrobial resistance. Effect of Adhatoda vasica massage in pyorrhoea. It was studied for antimicrobial, antioxidant, and anticancer activities. Sankar2 and K. Medicinal plants are important sources of practical drugs for people throughout the year.

Structure of the compounds: Antibacterial activities against Staphylococcus aureus and Micrococcus luteus were observed formethanolic extracts of all the above adhatodz plants. All melting point values are uncorrected and taken by open capillary method on a heating block Instrument. The solutions were filtered through a membrane filter pore size 0.

Vasicine acetate showed antimycobacterial activity [ 15 ]. Preliminary phytochemical and antibacterial screening of crude extract of the leaf of Adhatoda vasica. Nees Acanthaceaeknown commonly as Malabar nut tree, is a shrub growing throughout the Indian peninsula.

Essential oils of the leaves of A. Potent vaasica activity of alkaloid vasicine. Indian Journal of Natural Products and Resources. Glossary of Indian Medicinal Plants. The present studies cover antibacterial activity of the crude methanolic extracts of 11 medicinal plants viz. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Estimates of worldwide burden of cancer in Adhatoda vasica, Bauhenia variegate, Bombax ceiba, Carrisa opaca, Caryopteris grata, Debregeasia salicifolia, Lantana camara, Melia azedarach, Phyllanthus emblica, Pinus roxburghii and Olea ferruginea collected from lower Himalayas against two Gram positive Staphylococcus aureus, Micrococcus luteus and two Gram negative Escherichia coli, Pseudomonas aureginosa bacterial strains.

The physical and spectroscopic data were compared with those reported in the literature [ 2122 ]. HPLC analysis was carried out on a Waters Alliance separations module with photodiode vssica detector Waters, The emergence of drug-resistant pathogens and the increase in diseases affecting the immune system have greatly intensified the need to investigate new bioactive metabolites for potential pharmaceutical and industrial applications [ 12 ].

Antibacterial activity of adhatoda vasica leaf extract

Accumulation of vasicine sntibacterial vasicinone in tissue cultures of Adhatoda vasica and evaluation of the free radical-scavenging activities of the various crude extracts. Vasicine showed antimicrobial activity against S. Sample ethanol extract International Journal of Cancer.

A human adenocarcinoma cancer cell line was obtained from National Institute of Cell Sciences, Pune. Two mobile phases A and B were used at flow rate of 1.