Adhatoda vasica belonging to Acanthaceae family, commonly known as Adosa, Adhatoda vasica Flowers, Antibacterial activity, Antifungal activity, Diffusion. Abstract. The present study aimed to evaluate the in vitro antimicrobial activity of pharmacologically important Adhatoda vasica plant extracts. Antibacterial activity of leaf extract of Adhatoda vasica was studied against Bacillus subtilis, Antibacterial activity was determined by disc diffusion method.

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Vasicine acetate exhibited good zone of inhibition against bacteria: Sankar2 and K.

HPLC analysis was carried out on a Waters Alliance separations module with photodiode array detector Waters, It is inferred that methanolic crude extracts of the above mentioned plantsexhibitantibacterial activities against pathogenic bacteria, cativity proved atcivity ethnobotanical importance of the selected plants that indigenous people use for cure against various diseases. Vasicine is reported to have bronchodilatory, respiratory stimulant, and uterine stimulant effects [ 14 ]. The physical and spectroscopic data were compared with those reported in the literature [ 2122 ].

Antibacterial activity of adhatoda vasica leaf extract

A human adenocarcinoma cancer cell line was obtained from National Institute of Cell Sciences, Pune. The authors declare that there is no conflict of interests regarding the publication of this paper.


The plant is reported to show abortifacient [ 7 ], antimicrobial [ 89 ], and antitussive activities ahdatoda 10 ]. Cytotoxic A and antimicrobial effects of Methylobacterium sp. Antifeedant and toxic activity of Adhatoda vasica leaf extract against Spodoptera littoralis Lep.

Al-Dhabi1 C. Indian Journal adhatodq Medical Research.

Antibacterial Activity of Leaf Extracts of Adhatoda vasica – MAHE Digital Repository

Clinical and Laboratory Standards Institute; Table 2 Minimum inhibitory concentration of Actiity acetate against tested bacteria and fungi. It was then distilled on a water bath and the residue was washed with little n-hexane. Estimates of worldwide burden of cancer in International Journal of Crude Drug Research.

Asian Pacific Journal of Tropical Biomedicine. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The free radical scavenging activity was calculated as follows:. HPLC chromatograms of the ethanol extract of the leaves of Adhatoda vasica.

The solutions were filtered through a membrane antibacteriial pore size 0. Nees Acanthaceaeknown commonly as Malabar nut tree, is a shrub growing throughout the Indian peninsula.


In vitro antibacterial activity of selected medicinal plants from lower Himalayas.

The fraction was further purified and the compound Vasicine was isolated. The free radical scavenging activity was calculated as follows: Publications and Information Directorate; Indian Journal of Microbiology.

International Journal of Green Pharmacy. Published online Jan Zones of inhibition were recorded in millimetres and the experiment was repeated twice. Classical Uses of Medicinal Antibxcterial.

Accumulation of vasicine and vasicinone in tissue cultures of Adhatoda vasica and evaluation of the free radical-scavenging activities of the various crude extracts.

Mobile phase A consisted of water with 0. Antimycobacterial antibacteriap of two natural alkaloids, vasicine acetate and 2-acetyl benzylamine, isolated from Indian shrub Adhatoda vasica Ness. The spot turned orange red on spraying with Dragendorff’s reagent. Journal of Natural Product and Plant Resources.

The leaves are used to treat malarial fever, chronic fever, intrinsic hemorrhage, cough, asthma, leprosy, skin diseases, and piles [ 6 ].